Synthesis of high specific activity [14CO] methyl isocyanate and its use in the preparation of [14CO] eserine,[14CO] carbaryl and [14CO] IPMU

D Poullain, JP Noël

文献索引：Poullain; Noel Journal of Labelled Compounds and Radiopharmaceuticals, 1998 , vol. 41, # 5 p. 387 - 398

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被引用次数: 1

摘要

Abstract The preparation of [14 CO] methyl isocyanate from [1-14 C] acetyl chloride and activated sodium azide through the Curtius rearrangement was optimized (50% yield/[1-14 C] sodium acetate-50 mCi/mmol) and the reagent immediately used for the synthesis of [14 CO] eserine,[14 CO] carbaryl and [14 CO] IPMU.