Tetrahedron letters

Synthesis of methoxy and hydroxy containing tetralones: versatile intermediates for the preparation of biologically relevant molecules

A Ghatak, JM Dorsey, CM Garner, KG Pinney

文献索引：Ghatak, Anjan; Dorsey, James M.; Garner, Charles M.; Pinney, Kevin G. Tetrahedron Letters, 2003 , vol. 44, # 21 p. 4145 - 4148

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被引用次数: 19

摘要

The synthesis of 5-hydroxy-6-methoxy-1-tetralone and the 7-hydroxy regioisomer along with the corresponding 5, 7-dihydroxy analog has been achieved using an efficient directed metallation procedure followed by a regioselective methylene oxidation. This ...