Cyclization of 2??benzoylamino??N??methyl??thiobenzamides to 3??methyl??2??phenylquinazolin??4??thiones

J Hanusek, P Drabina, MŠ Sedlák…

文献索引：Hanusek, Jiri; Rosa, Pavel; Drabina, Pavel; Sedlak, Milos Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 5 p. 1281 - 1285

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被引用次数: 5

摘要

Quinazoline-4-ones and their derivatives are well known for their pharmacological activity [1]. Their synthesis mostly starts from anthranilic acid derivatives, in particular their N- acylamides [2, 3]. The aim of the present work is to synthesize the sulfur analogues of N- benzoylaminoanthranilamides and to carry out their ring closure to the corresponding 2- phenyl-3-methylquinazoline-4-thiones, which could show biological activity too [4, 5]. ...