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Heterocycles

Synthesis of 8, 9, 10, 11-tetrahydroindolo [2, 1-c] benzo [1, 2, 4]-triazine. A new ring system

…, A Montalbano, AM Almerico, G Dattolo, G Cirrincione

文献索引:Barraja, Paola; Diana, Patrizia; Lauria, Antonino; Montalbano, Alessandra; Almerico, Anna Maria; Dattolo, Gaetano; Cirrincione, Girolamo Heterocycles, 2003 , vol. 60, # 11 p. 2519 - 2525

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被引用次数: 2

摘要

Résumé/Abstract Indolo [2, 1-c] benzo [1, 2, 4] triazine, a new ring system, was synthesized by diazotization of 2-amino-1 aryltetrahydroindoles followed by an intramolecular coupling of the diazonium group with the aryl moiety. All the new compounds were screened at the NCI for antiproliferative property but none of them showed significant activity.