Journal of Heterocyclic Chemistry

Synthesis of 2??substituted??5??rnethylthiazolo [3, 2??b]??1, 2, 4??lriazoles and acylatcd 3??amino??2??imino??4??methyl??2??thiazolines

K Pilgram, GE Pollard

文献索引：Pilgram,K.; Pollard,G.E. Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 1225 - 1228

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被引用次数: 11

摘要

Abstract 3-Amino-2-imino-4-mcthyl-2-thiazoline, 1, underwent ring closure with ethyl formate, cyanogen bromide and carbon disulfide, giving moderate yields of 2-substituted-5- methylthiazolo [3, 2-b]-1, 2, 4-triazoles, II. Reaction of I-HCl with acid anhydrides (acetic, propionie, trifluoroacetic) resulted in the formation of the corresponding II compounds, whereas other anhydrides (benzoic, perfluoropropionic, perfluorobutyric) gave high yields ...