Highly Enantioselective Diels− Alder Reactions of Danishefsky Type Dienes with Electron-Deficient Alkenes Catalyzed by Yb (III)-BINAMIDE Complexes

…, D Shirasaki, S Harada, A Nishida

文献索引：Sudo, Yukinori; Shirasaki, Daisuke; Harada, Shinji; Nishida, Atsushi Journal of the American Chemical Society, 2008 , vol. 130, # 38 p. 12588 - 12589

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被引用次数: 46

摘要

1-Methoxy-3-trimethylsiloxy-1, 3-butadiene (Danishefsky's diene) is recognized as a synthetically useful diene due to its high reactivity in the Diels− Alder reaction with electron- deficient alkenes to give oxygen-functionalyzed cyclohexenes and substituted cyclohexenones, which are important building blocks for the total synthesis of natural products. However, the development of catalytic enantioselective versions of Diels− Alder ...