Zinc??Catalyzed Amide Cleavage and Esterification of β??Hydroxyethylamides

…, Y Nishii, T Higuchi, K Mashima

文献索引：Kita, Yusuke; Nishii, Yuji; Higuchi, Takafumi; Mashima, Kazushi Angewandte Chemie - International Edition, 2012 , vol. 51, # 23 p. 5723 - 5726

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被引用次数: 27

摘要

Amides are ubiquitous in nature and have extremely stable bonds, as their half-life for spontaneous hydrolysis is estimated to be 350 to 600years at neutral pH and room temperature.[1] In the biological metabolic cycle in nature, in contrast to the relatively easy formation of amides, the cleavage (hydrolysis) of amide bonds is an energy-consuming, ATP- dependent event that requires enzymes.[2] In chemical evolution in the pre-enzyme era, ...

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Potassium phosphate/benzyltriethylammonium chloride as effic...

[Cepanec, Ivica; Zivkovic, Andreja; Bartolincic, Anamarija; Mikuldas, Hrvoje; Litvic, Mladen; Merkas, Sonja Croatica Chemica Acta, 2008 , vol. 81, # 3 p. 519 - 523]