Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The total synthesis of the antiparasitic spiroketal macrolide (+) milbemycin α 1 is reported, following Julia sulfone anion coupling of the sulfone 3 with a northern hemisphere aldehyde 2 and subsequent functional group elaboration. ... The total synthesis of the antiparasitic spiroketal ...