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Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes

GR Bebernitz, V Beaulieu, BA Dale…

文献索引:Journal of Medicinal Chemistry, , vol. 52, # 19 p. 6142 - 6152

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被引用次数: 69

摘要

... Journal of Medicinal Chemistry. ... 10−15 years. Glucokinase (GK) activators are currently under investigation by a number of pharmaceutical companies with only a few reaching early clinical evaluation. A GK activator ...