Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives

M Xu, J Zhu, Y Diao, H Zhou, X Ren…

文献索引：Faull, Alan W.; Hull, Roy Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1078 - 1082

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被引用次数: 14

摘要

... Journal of Medicinal ... 20), pp 7911–7924. DOI: 10.1021/jm400938g. Publication Date (Web): September 27, 2013. Copyright © 2013 American Chemical Society. ... caused by Plasmodium parasites, among which Plasmodium falciparum is the most dangerous one, with the highest ...