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Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, …

PL Ornstein, MB Arnold, NK Allen…

文献索引:Journal of Medicinal Chemistry, , vol. 39, # 11 p. 2232 - 2244

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被引用次数: 43

摘要

... Journal of Medicinal Chemistry. ... Our medicinal chemistry research efforts are targeted toward the identification of compounds which are potent and selective antagonists of excitatory amino acid (EAA) receptors, 1 with the goal of developing these compounds as novel ... Chemistry. ...