Enol Esters. II. 1a N-Acylation of Amides and Imides

ES Rothman, S Serota, D Swern

文献索引：Rothman,E.S. et al. Journal of Organic Chemistry, 1964 , vol. 29, p. 646 - 650

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被引用次数: 20

摘要

An improved method for X-acylation of certain amides and imides has been developed. Brief fusion of a mixture of isopropenyl stearate and acid catalyst with cyclic imides (succinimide, maleimide, phthalimide, barbituric acids), cyclic imide-amides (spirohydantoins), N-alkyl amides, or N-aryl amides causes elimination of acetone as the temperature exceeds 150- 175'and gives high yields of X-acylated products. N-Stearoylsuccinimide (I) undergoes ...