Synthesis of 1, 4, 5-Trisubstituted 1, 2, 3-Triazoles Amicable for Automation

…, PS Mainkar, S Chandrasekhar

文献索引：Kavitha, Mitta; Mahipal, Bodugam; Mainkar, Prathama S.; Chandrasekhar, Srivari Combinatorial Chemistry and High Throughput Screening, 2013 , vol. 16, # 8 p. 657 - 663

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被引用次数: 1

摘要

A three-component 3+ 2 cycloaddition reaction followed by Suzuki coupling reaction was carried out to synthesize a library of compounds using automation (parallel synthesizer). Scaffolds that are unexplored in literature were used for the synthesis of library. The iodo- triazoles formed by 3+ 2 cycloaddition reaction were coupled with boronic acids to get tri- substituted triazoles.