Solid state NMR studies of oligourea foldamers: Interaction of 15 N-labelled amphiphilic helices with oriented lipid membranes

…, N Pendem, G Guichard, B Bechinger

文献索引：Aisenbrey, Christopher; Pendem, Nagendar; Guichard, Gilles; Bechinger, Burkhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 7 p. 1440 - 1447

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被引用次数: 13

摘要

Synthetic oligomers that are derived from natural polypeptide sequences, albeit with unnatural building blocks, have attracted considerable interest in mimicking bioactive peptides and proteins. Many of those compounds adopt stable folds in aqueous environments that resemble protein structural elements. Here we have chemically prepared aliphatic oligoureas and labeled them at selected positions with 15N for structural ...