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Structure–activity relationship studies of novel 3-oxazolidinedione-6-naphthyl-2-pyridinones as potent and orally bioavailable EP 3 receptor antagonists

ÁI Morales-Ramos, YH Li, M Hilfiker, JS Mecom…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2806 - 2811

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被引用次数: 5

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 27 Herein, we describe our detailed SAR studies and optimization of multiple regions of this chemical series that resulted in the identification of lead compounds such as compound 29. ...