Abstract Eleven symmetrically 2, 6-disubstituted benzoic acids (with the following substituents: OCH 3, OC 2 H 5, OC 3 H 7, OCH (CH 3) 2, OC 4 H 9, CH 3, F, Cl, Br, I, and NO 2) have been synthesized and their dissociation constants measured potentiometrically in methanol, ethanol, propan-1-ol, propan-2-ol, butan-2-ol, acetone, dimethyl sulfoxide, dimethylformamide, acetonitrile, pyridine, and 1, 2-dichloroethane. The experimental data ...