Selection and Scale-Up Evaluation of an Alternative Route to (−)-(3 R, 4 R)-1-Benzyl-4-(benzylamino) piperidin-3-ol

IS Young, A Ortiz, JR Sawyer, DA Conlon…

文献索引：Wang, Dengjin; Nugent, William A. Journal of Organic Chemistry, 2007 , vol. 72, # 19 p. 7307 - 7312

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被引用次数: 6

摘要

... Select a Journal or Book ... Organic Process Research ... Charging an ethanol solution of sodium borohydride (0.25 mmol, 10 mol %) to a solution of 23 (2.5 mmol) in ethanol at 10 °C (mode A, Scheme 2) generated 79 J over a 6 min reaction time (Figure 3). In the reverse mode ...