A switch in enantiomer preference between mitochondrial F 1 F 0-ATPase chemotypes

…, A Pudzianowski, H Monshizadegan, P Wang…

文献索引：Bisaha, Sharon N.; Malley, Mary F.; Pudzianowski, Andrew; Monshizadegan, Hossain; Wang, Paulina; Madsen, Cort S.; Gougoutas, Jack Z.; Stein, Philip D. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 11 p. 2749 - 2751

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被引用次数: 21

摘要

The preferred absolute configuration of two series of F 1 F 0 -ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same 'triaryl' pharmacophore to the enzyme binding site. ... The preferred absolute configuration of two series of F 1 F 0 -ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents ...