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Journal of fluorine chemistry

Facile synthesis of α-fluoro substituted amidines from imidoyl chlorides and some of its application

YM Wu, M Zhang, YQ Li

文献索引:Wu, Yong-Ming; Zhang, Min; Li, Yi-Qun Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1168 - 1174

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被引用次数: 11

摘要

Amidines, the nitrogen analogues of carboxylic acids, are structural parts of numerous compounds of biological interest including important medical and biochemical agents. They are used as trypsin inhibitors [1], platelet fibrinogen receptor antagonists [2], VLA-4 antagonists [3], etc. Besides