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Diastereoselective synthesis of 2-isoxazolines via silaketal tethered 1, 3-dipolar cycloadditions

H Marrugo, R Dogbéavou, L Breau

文献索引：Dogbeavou, Romain; Breau, Livain Synlett, 1997 , vol. 1997, # 10 p. 1208 - 1210

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被引用次数: 14

摘要

The use of silaketals derived from allylic alcohols and 1-substituted nitroethanols for the stereocontrolled synthesis of 3, 4, 5-trisubstituted 2-isoxazolines via intramolecular 1, 3- dipolar cycloaddition is demonstrated. High levels of stereoselectivity (70–92% de) were