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Catalytic Enantioselective Iodocyclization of γ-Hydroxy-cis-alkenes

SH Kang, SB Lee, CM Park

文献索引:Kang, Sung Ho; Lee, Sung Bae; Park, Chul Min Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15748 - 15749

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被引用次数: 147

摘要

Enantioselective iodocyclization of γ-hydroxy-cis-alkenes has been achieved using I2 in the presence of an unprecedented catalyst system generated from (R, R)-t-Bu-salen-Co (II) complex and NCS to produce 2-monosubstituted tetrahydrofurans up to 90% ee. While ...