Novel cyclodextrin-oligosiloxane copolymers for use as stationary phases to separate enantiomers in open tubular column supercritical fluid chromatography

G Yi, JS Bradshaw, BE Rossiter, SL Reese…

文献索引：Yi, Guoliang; Bradshaw, Jerald S.; Rossiter, Bryant E.; Reese, Shawn L.; Petersson, Patrik; et al. Journal of Organic Chemistry, 1993 ,  vol. 58,  # 9  p. 2561 - 2565

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被引用次数: 51

摘要

Five novel 8-(or CY-) cyclodextrin-hexasiloxane copolymers have been prepared by a seven- (or nine-) step process. A key step was the reaction of partially alkylated 8-(or CY-) cyclodextrin (8, 9, or 10) with p, p'-methylenebis (benzenesulfony1 chloride) to form a bissulfonate ester on the smaller rim of cyclodextrin. These bissulfonates were reacted with sodium p-(ally1oxy) phenoxide followed by alkylation to form the peralkylated bis ( ...