Stereoselective synthesis of disubstituted 3 (2H)-furanones via catalytic intramolecular CH insertion reactions of α-diazo-β-keto esters including asymmetric induction
T Ye, MA McKervey, BD Brandes, MP Doyle
文献索引：Brandes, Bridget D. Tetrahedron Letters, 1994 , vol. 35, # 39 p. 7269 - 7272
Abstract Rhodium (II) catalysed decomposition of γ-alkoxy-α-diazo-β-ketoesters produce cis- 2, 5-disubstituted-3 (2H)-furanones with high (> 97%) stereoselectivity. The combination of a chiral auxiliary in the ester moiety of the diazo precursor and a chiral catalyst can lead to
