Synthesis of the 7??Azaindole (1 H??Pyrrolo [2, 3??b] pyridine) Analogous to Cannabimimetic JHW 200

S Gluszok, L Goossens, P Depreux…

文献索引：Gluszok, Sebastien; Goossens, Laurence; Depreux, Patrick; Barbry, Didier; Henichart, Jean-Pierre Synthetic Communications, 2006 , vol. 36, # 19 p. 2797 - 2805

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被引用次数: 4

摘要

Abstract Cannabinoid agonists have been suggested to have potential therapeutic uses. The synthesis of a new cannabimimetic analogue of JHW 200 possessing a 7??azaindole unit instead of an indole moiety is described. The approach used for indole derivatives failed, and a new strategy that involves the reaction of a nitrile and 1??naphtyl magnesium bromide was studied.