Isosteres of natural phosphates. 2. Synthesis of the monosodium salt of 4-hydroxy-3-oxobutyl-l-phosphonic acid an isostere of dihydroxyacetone phosphate
SL Goldstein, D Braksmayer, BE Tropp…
文献索引：Goldstein,S.L. et al. Journal of Medicinal Chemistry, 1974 , vol. 17, p. 363 - 364
of dihydroxyacetone phosphate, was undertaken. Concurrently, a route for the synthesis of 3, 4-dihydroxybutyl-1-phosphonic acid (8) was sought which would be readily applicable to the incorporation of a radioactive label (tritium) into the molecule. These two routes are described below.
