前往化源商城

Synthesis of 3-(aminoalkyl)-1-[(5-nitrofurfurylidene) amino] hydantoins

CF Spencer, JG Michels, GC Wright…

文献索引:Spencer,C.F. et al. Journal of Medicinal Chemistry, 1973 , vol. 16, p. 953 - 956

全文:HTML全文

被引用次数: 1

摘要

Biologic Activity. The compounds were tested for antibacterial activity in vitro by reported procedure~.~ Although no real trend is apparent, inspection of Table I1 shows that compounds with an alkyl chain of 3-5 carbon atoms appear most active against Staphylococcus aureus, Escherichia coli, and Streptococcus pyogenes. The piperidino, morpholino, and pyrrolidino analogs, however, all have about the same order of activity ...