Reversible monoamine oxidase inhibitors in the indolinone series
DG Tsedere, BA Grinberg, AS Roska, LM Zorin…
文献索引：Tsedere, D. G.; Grinberg, B. A.; Roska, A. S.; Zorin, L. M.; Zhungietu, G. I.; Prikulis, A. A. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 5 p. 304 - 307 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 5 p. 555 - 558
Most of the MAO inhibitors investigated thus far are characterized by pronounced toxic- ity to the organism [3], and their high anti-MAO activity is often associated with irreversi- bility of their activity, which prevents their pharmacological application. In order to search for new reversible and less toxic MAO inhibitors we investigated a number of indoline-2,3-dione (isatin) derivatives. Several relationships between the anti-MAO activity and the structure of the ...
