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Incorporation of molecular nitrogen into organic compounds. 2. Novel lactam synthesis by use of a combination system of carbonylation and nitrogenation

Y Uozumi, N Kawasaki, E Mori, M Mori…

文献索引:Uozumi, Yasuhiro; Kawasaki, Naofumi; Mori, Eiko; Mori, Miwako; Shibasaki, Masakatsu Journal of the American Chemical Society, 1989 , vol. 111, # 10 p. 3725 - 3727

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被引用次数: 52

摘要

Abstract: An amide unit was constructed from aryl halide and titanium-isocyanate complex prepared from Tiel4 under atmospheric pressure of molecular nitrogen and carbon monoxide in the presence of a palladium catalyst. With this combination system of carbonylation and nitrogenation, isoindolinone and quinazolinone derivatives were synthesized from o-halophenyl alkyl ketone in one step. The reaction proceeds through ...