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Nucleosides. 130. Synthesis of 2′??Deoxy??2′??substituted??and 5′??Deoxy??5′??substituted?螃??uridine Derivatives. Crystalline and Molecular Structure of 2′??Chloro …

KW Pankiewicz, KA Watanabe…

文献索引:Pankiewicz; Watanabe; Takayanagi; et al. Journal of Heterocyclic Chemistry, 1985 ,  vol. 22,  # 6  p. 1703 - 1710

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被引用次数: 13

摘要

Abstract A method was developed to prepare 5′-deoxy-5′-substituted-ψ-uridine derivatives 4 from 3′, 5′-O-(1, 1, 3, 3-tetraisopropyldisiloxanyl)-1, 3-dimethyl-ψ-uridine 1 via a silyl rearrangement reaction. Nucleophilic displacement of the mesyloxy function of 2 ...