Abstract Some derivatives of benzyloxycarbonylated 3, 6-diisopropyl-2-hydroxypyrazine and 3, 6-diisopropyl-2-pyrazinethiol were prepared and shown to be the versatile benzyloxycarbonylation reagents for amines and amino acids. It was also ascertained that 3, 6-diisopropyl-2-hydroxypyrazine and 3, 6-diisopropyl-2-pyrazine-thiol serve effectively as carriers of the β, β, β,-trichloroethoxycarbonyl group.