Asymmetric Hydrosilylation of Ketones Using Trans-Chelating Chiral Peralkylbisphosphine Ligands Bearing Primary Alkyl Substituents on Phosphorus Atoms.

…, M Sawamura, J Shirai, M Takahashi, Y Ito

文献索引：Kuwano, Ryoichi; Sawamura, Masaya; Shirai, Junya; Takahashi, Masatoshi; Ito, Yoshihiko Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 2 p. 485 - 496

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被引用次数: 65

摘要

Asymmetric hydrosilylation of simple ketones with diphenylsilane proceeded at-40° C in the presence of a rhodium complex (0.001—0.01 molar amount) coordinated with a trans- chelating chiral bisphosphine ligand bearing linear alkyl substituents on the phosphorus atoms,(R, R)-(S, S)-Et-, Pr-, or BuTRAP, giving the corresponding optically active (S)- secondary alcohols with up to 97% ee. The asymmetric hydrosilylation using TRAP ...