Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs

…, A Geronikaki, P Zoumpoulakis, C Camoutsis…

文献索引：Omar, Kouatli; Geronikaki, Athina; Zoumpoulakis, Panagiotis; Camoutsis, Charalabos; Sokovic, Marina; Ciric, Ana; Glamoclija, Jasmina Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 1 p. 426 - 432

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被引用次数: 177

摘要

As part of ongoing studies in developing new antimicrobials, a class of structurally novel 4- thiazolidinone derivatives incorporating three known bioactive nuclei such as thiazole, thiazolidinone and adamantane was synthesized by the multi-step reaction protocol, already reported in the literature. NMR and Molecular Modeling techniques were employed for structure elucidation and Z/E potential isomerism configuration of the analogues. ...