Synthesis and biological evaluation of pyrido [3′, 2′: 4, 5] furo [3, 2-d] pyrimidine derivatives as novel PI3 kinase p110α inhibitors

M Hayakawa, H Kaizawa, H Moritomo…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 9 p. 2438 - 2442

全文：HTML全文

被引用次数: 116

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 24 and 25 In screening our chemical library, we identified 2a as another lead compound with structural similarity to 1. Through structural modification of 2a, the novel pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine 10e was identified as a ...