Synthesis of some halogen-and nitro-substituted nicotinic acids and their fragmentation under electron impact

…, VD Strelkov, SN Mikhailichenko, VN Zaplishny

文献索引：Dyadyuchenko; Strelkov; Mikhailichenko; Zaplishny Chemistry of Heterocyclic Compounds, 2004 , vol. 40, # 3 p. 308 - 314

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被引用次数: 4

摘要

Abstract Features of electrophilic and nucleophilic substitution under chlorination and nitration reactions conditions have been investigated for 6-hydroxy-and 6-methyl-substituted derivatives of 3-cyano-4-methyl-2 (1H)-pyridones. The polychloro-and nitro-substituted 3- cyano-4-methylpyridines obtained were used as synthons in the synthesis of some polyhalo- and nitro-substituted nicotinic acids and their amides. The fragmentation pathways of the ...