Tetrahedron letters

An efficient copper-catalyzed N-arylation of pyridazinones with a structurally well-defined copper complex

YM Pu, YY Ku, T Grieme, R Henry, AV Bhatia

文献索引：Pu, Yu-Ming; Ku, Yi-Yin; Grieme, Tim; Henry, Rodger; Bhatia, Ashok V. Tetrahedron Letters, 2006 , vol. 47, # 2 p. 149 - 153

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被引用次数: 36

摘要

N-Arylation of pridazinone derivatives with an aryl or heteroaryl bromide or iodide has been achieved in 70–94% isolated yield using catalytic amounts of the stable and structurally well defined copper catalyst under standard Ullmann–Goldberg reaction conditions. The structure of copper catalyst was characterized by ESI-MS, DSC and the single crystal X-ray.