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Tetrahedron Letters

Amidoalkylation of dienes with adducts of glyoxylic-synthesis of α-acylamino-γ-alkenyl-γ-butyrolactones

D Ben-Ishai, S Hirsch

文献索引:Ben-Ishai, D.; Hirsch, S. Tetrahedron Letters, 1983 , vol. 24, # 9 p. 955 - 958

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被引用次数: 15

摘要

Abstract Amidoalkylation of 1, 3-dienes with the adduct of glyoxylic acid-methyl carbamate (1) afforded α-acylamino-γ-alkenyl-γ-butyrolactones (eg 2, 6-9) in 40–80% yield and the pipecolic acid derivatives (eg 3) in less than 20% yield. An explanation is suggested to account for above results.