Ruthenium-catalyzed reduction of allylic alcohols: An efficient isomerization/transfer hydrogenation tandem process

V Cadierno, J Francos, J Gimeno…

文献索引：Cadierno, Victorio; Francos, Javier; Gimeno, Jose; Nebra, Noel Chemical Communications, 2007 , # 24 p. 2536 - 2538

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被引用次数: 36

摘要

Herein, we report a simple and highly efficient method for the selective reduction of the C C bond in allylic alcohols, based on a novel ruthenium-catalyzed tandem process (Scheme 1). This one-pot transformation involves the initial isomerization of the allylic alcohol and subsequent transfer hydrogenation (TH) of the resulting carbonyl compound. A series of ruthenium complexes are well known catalysts for performing both individual steps with high efficiency. 4,5 The ...