Parallel synthesis of an oligomeric imidazole-4, 5-dicarboxamide library

Z Xu, JC DiCesare, PW Baures

文献索引：Xu, Zhigang; DiCesare, John C.; Baures, Paul W. Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 248 - 254

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被引用次数: 7

摘要

A library of oligomeric compounds based on the imidazole-4, 5-dicarboxylic acid scaffold with incorporated amino acids were synthesized, purified, and characterized. These compounds are hypothesized to inhibit protein− protein interactions and are being used for high-throughput screening in the NIH Roadmap.