Tetrahedron Letters

Introduction of α-(acyl) methylthiomethyl group into the aromatic ring by Friedel-Crafts reaction

Y Tamura, H Shindo, J Uenishi, H Ishibashi

文献索引：Tamura, Y.; Shindo, H.; Uenishi, J.; Ishibashi, H. Tetrahedron Letters, 1980 , vol. 21, p. 2547 - 2548

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被引用次数: 27

摘要

Abstract Friedel-Crafts α-(acyl) methylthiomethylations of aromatic compounds with α- ethoxycarbonyl,-acetyl,-benzoyl, and-cyano-α-(methylthio) methyl chlorides are described. The resulted products are easily converted to acylmethylated aromatics such as phenylacetate and phenylacetone by reductive desulfurization.