To evaluate and compare the microleakage of various restorative materials used as coronal barriers between endodontic appointments.Eighty extracted human permanent posterior teeth were prepared for standardized access cavities with dimensions of 4 × 4 × 4 mm. The teeth were then randomly divided into four groups; Kalzinol, Caviton, GC Fuji IX and GC Fuji II LC. After incubation, the samples were immersed in 2% methylene blue for 7 days. The depth of penetration was measured using a digital macroscope after longitudinal sectioning of each tooth. Kruskal-Wallis (p < 0.05) and multiple Mann-Whitney test with Bonferroni correction (p < 0.008) were used for data analysis.The degree of microleakage varied at the material/ tooth interface among the test materials, and the difference was statistically significant (p < 0.05). GC Fuji II LC group showed the least median microleakage value (0.8105 ± 0.305), followed by Caviton (1.1885 ± 0.396), GC Fuji IX (3.3985 ± 0.305) and Kalzinol (4.161 ± 0.853).Within the limitations of this study, GC Fuji II LC exhibited the best marginal seal, and has the potential to be used as a suitable coronal barrier between endodontic appointments.Given the prime importance that dental practitioners should thoroughly restore any tooth with a suitable coronal barrier between endodontic appointments, this study shows that Fuji II LC has the ability to maintain a hermetic seal for 7 days.
