New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno [2, 3-b] thiophene-2-sulfonamides and 5-substituted …

JD Prugh, GD Hartman, PJ Mallorga…

文献索引：Journal of Medicinal Chemistry, , vol. 34, # 6 p. 1805 - 1818

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被引用次数: 99

摘要

... of the compound to concentrate in the iris plus ciliary body;I3 for sensitization liability in the guinea pig maximum sensi- tization test14 (GPMST); mutagenic liability in the Ames test;15 and pharmaceutical formulateability.16 At ... 1810 Journal of Medicinal Chemistry, 1991, Vol. ...