Journal of medicinal chemistry

Synthesis and antitumor and antibacterial activity of benzoquinones related to the mitomycins

TR Witty, WA Remers

文献索引：Witty,T.R.; Remers,W.A. Journal of Medicinal Chemistry, 1973 , vol. 16, p. 1280 - 1284

全文：HTML全文

被引用次数: 17

摘要

HI (30 ml) at 60" for 28 hr when no CO2 was detected in the effluent gases. The clear solution was extracted with CHC13 (3 Y. 15 mli and concentrated in Vacuo to an oil, which solidified when digested with Et20 (4 X 30 ml). The product (0.3 g, 39%) was washed with Et20 several times to vield the analytical sample: mp 104" dec. Ana/.(C~ H~ INOS) C. S: H: calcd. 3.14: found. 3.62; I: calcd. 49.36; found. 51.75,