Organic Letters 2011-03-18

Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon.

Ganesan Gobi Rajeshwaran, Arasambattu K Mohanakrishnan

文献索引：Org. Lett. 13(6) , 1418-21, (2011)

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摘要

A synthesis of staurosporine aglycon and its analogs was achieved in a 28-36% overall yield starting from 2-methylindole. The prominent key steps for the synthesis of the indolocarbazole alkaloids involved electrocyclization and nitrene insertion reactions.