Asymmetrische Katalysen: XXX. Enantioselektive hydrierung von crotonsäurederivaten mit rhodium-phosphin-katalysatoren

H Brunner, A Knott, M Kunz, E Thalhammer

文献索引：Brunner, Henri; Knott, Alfons; Kunz, Manfred; Thalhammer, Elisabeth Journal of Organometallic Chemistry, 1986 , vol. 308, p. 55 - 62

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被引用次数: 3

摘要

Abstract The Z-and E-isomers of the α-N-benzoylamino-2-butenoic acid methyl ester, the E/Z mixtures of α-N-benzoylamino-2-butenoic acid, and the Z-form of α-N-acetylamino-2- butenoic acid were hydrogenated enantioselectively. The hydrogenation products are derivatives of α-aminobutyric acid, which can be reduced to aminobutanol, the optically active component of the antituberculosis drug (+)-ethambutol. In situ catalysts consisting of ...