Extension of the Heck reaction to the arylation of activated thiophenes

L Lavenot, C Gozzi, K Ilg, I Orlova, V Penalva…

文献索引：Lavenot; Gozzi; Ilg; Orlova; Penalva; Lemaire Journal of Organometallic Chemistry, 1998 , vol. 567, # 1-2 p. 49 - 55

全文：HTML全文

被引用次数: 100

摘要

The direct arylation of activated thiophenes was accomplished in moderate to good yields using a Heck-type reaction with the mixture of Pd (OAc) 2 and n-Bu4NBr as a catalytic system. This new arylation method is applied to different derivatives and has proved to be compatible with sensitive functional groups. Furthermore, the substituent nature and position on the thiophene moiety influence the cross coupling. In particular the substitution is ...