Molecular BioSystems 2013-05-01

Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit.

Yeon Hee Ban, Jong Hyun Lee, Gyo Rim Gu, Boram Lee, SangJoon Mo, Ho Jeong Kwon, Yeo Joon Yoon

文献索引：Mol. Biosyst. 9(5) , 944-7, (2013)

摘要

A FK506 analogue containing a non-natural starter unit was obtained through mutasynthesis by feeding cultures of Streptomyces sp. KCTC 11604BP fkbO deletion mutant with 3-cyclohexene-1-carboxylic acid. The structure of the new compound, 32-dehydroxy-FK506, and its biological activities were determined.

结构式	名称/CAS号	分子式	全部文献
	3-环己烯-1-甲酸 CAS:4771-80-6	C₇H₁₀O₂

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Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit.

摘要

相关化合物