Practical method for the synthesis of D-or L-. alpha.-amino acids by the alkylation of (+)-or (-)-pseudoephedrine glycinamide.

AG Myers, JL Gleason, T Yoon

文献索引：Myers, Andrew G.; Gleason, James L.; Yoon, Taeyoung Journal of the American Chemical Society, 1995 , vol. 117, # 32 p. 8488 - 8489

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被引用次数: 119

摘要

The central role of a-amino acids in chemistry and biology has stimulated the development of numerous methods for their synthesis.'Among these, the asymmetric alkylation of chiral glycine derivatives, conceptually one of the simplest and most general strategies, figures prominently. 2 In this work we detail a new method for the synthesis of D-or La-amino acids that involves the direct alkylation of (+)-or (-)-pseudoephedrine glycinamide, without the ...

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