The preparation of 2, 4-diethoxy-6-pyrimidylmagnesium bromide and 2,~-dietlioxy-G- pyrinlid~ llitl1iurn is described. 2, 4-Diethoxy-6-pyrimidylcarbinols obtained from the latter have been converted by successive oxidation and hydrolysis into 6-acyluracils. Carbonation of the lithium compound with C1* O~ and hydrolysis of the product gave orotic acid-C1lOzH.