Semisynthetic cephalosporins. Synthesis and structure-activity relations of analogs with 7-acyl groups derived from 2-(cyanomethylthio) acetic acid or 2-[(2, 2, 2- …

RM DeMarinis, JC Boehm, GL Dunn…

文献索引：Journal of Medicinal Chemistry, , vol. 20, # 1 p. 30 - 35

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被引用次数: 11

摘要

... 2-(Cyanomethylthio)acetic Acid (1). In 200 ml of HzO was dissolved 16 g (0.4 mol) of NaOH and 18.4 g (0.2 mol) of mer- captoacetic acid. The solution was cooled to room temperature, Page 5. 34 Journal of Medicinal Chemistry, 1977, Vol. 20, No. 1 ...