Tetrahedron letters

Acetoxylation of 6, 7-dialkoxy-substituted 1, 4-dihydroquinoxaline-2, 3-diones (Qxs) using fuming nitric acid in acetic acid: A facile synthesis of 5-acyloxy-6, 7-dialkoxy …

ZL Zhou, E Weber, JFW Keana

文献索引：Zhou, Zhang-Lin; Weber, Eckard; Keana, John F. W. Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7583 - 7586

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被引用次数: 9

摘要

Treatment of 6, 7-dialkoxy-1.4-dihydroquinoxaline-2.3-diones 3 with fuming nitric acid in acetic acid at 25° C resulted in an acetoxylation reaction, giving 5-acetoxy-6, 7-dialkoxy-1, 4- dihydroquinoxaline-2. 3-diones 4 in moderate yields A mechanism involving ipso attack of nitronium ion as the first step is proposed.